All rights reserved. If so, it’s important that you tell your doctor or pharmacist before you start donepezil. Gas 16. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Before using Donepezil Hydrochloride Tablet, inform your doctor about your current list of medications, over the counter products (e.g. Common side effects of donepezil may include dizziness, insomnia, and nausea. Side effects not requiring immediate medical attention. O 0. Medicines to treat challenging behaviour Bleeding Of The Stomach Or Intestines 6. Pfizer US Pharmaceuticals, New York, NY. Other side effects include: fatigue, muscle cramps, vomiting, weight loss, anorexia, and ecchymoses. Neurology 61 (2003): 1452, 7. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Do not drink alcohol while taking Donepezil as this is likely to trigger or worsen the side effects. Trouble sleeping can be a side effect of donepezil but should subside with continued use. Other side effects include muscle cramps, headaches, dizziness, fatigue and insomnia. J Clin Psychiatry 62 (2001): 573-4, 10. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. The most common side effects of donepezil are diarrhoea, headache and feeling sick (nausea). Heart Block 17. Dementia 7 (1996): 293-303, 6. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. You can take it with or without food. Excessive Sweating 13. Rozzini L, Ghianda D, Trabucchi M, Padovani A "Severe worsening of parkinsonism in Lewy body dementia due to donepezil." What should I know about storage and disposal of this medication? Donepezil may cause side effects such as dizziness or tiredness. Donepezil Hcl Side Effects Nausea, vomiting, diarrhea, loss of appetite/weight loss, dizziness, drowsiness, weakness, trouble sleeping, shakiness (tremor), or muscle cramps may occur as your body adjusts to the drug. It is unknown if Aricept is harmful to a fetus. Usar un AINE con donepezil puede aumentar su riesgo de úlcera gástrica. 4. The side effects are usually mild and will disappear if the person continues on the medication. Extreme Loss Of Body Water 14. Some clastogenic effects were observed in vitro at concentrations overtly toxic to the cells and more than 3000 times the steady-state plasma concentrations. Get medical help right away if you have any very serious side effects, including: slow/fast/irregular heartbeat, severe dizziness, fainting. Donepezil is indicated for the treatment of dementia of the Alzheimer's type. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, burning, prickling, or tingling sensations, increased urge to urinate during the night, mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness, pains in stomach, side, or abdomen, possibly radiating to the back, seeing, hearing, or feeling things that are not there. Donepezil increases the levels of a substance (acetylcholine) in the brain involved in memory function Donepezil should not be taken with other medicines that increase the activity of acetylcholine, as this may increase the risk of side effects. J Am Geriatr Soc 57 (2009): 565. If experienced, these tend to have a Severe expression 1. Cataracts 9. Donepezil oral tablet doesn’t cause drowsiness, but it can cause other side effects. What other drugs will affect donepezil? More common side effects. The side effects of memantine are less common and less severe than for the cholinesterase inhibitors. Distribution: Volume of distribution: 12-16 L/kg. Last updated on Oct 25, 2020. Donepezil is predicted to decrease the effects of cisatracurium. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. J Neurol Neurosurg Psychiat 66 (1999): 410, 11. Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. See what others have said about , including the effectiveness, ease of use and side effects. This is not a complete list of side effects with Donepezil hydrochloride tablets. Amouyal-Barkate K, Bagheri-Charabiani H, Montastruc JL, Moulias S, Vellas B "Abnormal movements with doneprzil in Alzheimer disease." Serious side effects: Other side effects include: dizziness, nausea, vomiting, anorexia, and ecchymoses. 3. pregnancy, upcoming surgery, etc. Some side effects may not be reported. donepezil, memantine, Aricept, Namenda, rivastigmine, Exelon. Most adverse events are mild in severity and transient in nature. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for DONEPEZIL HYDROCHLORIDE. See below for a comprehensive list of adverse effects. DRESS Syndrome 12. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Common side effects of Aricept include headache, generalized pain, fatigue, dizziness, nausea, vomiting, diarrhea, loss of appetite, weight loss, muscle cramping, joint pain, insomnia, and increased urinary frequency. What are the side effects? The more common side effects that can … Check with your doctor as soon as possible if any of the following side effects occur while taking donepezil: Frequency of common adverse effects may be influenced by the rate of titration. Like all medicines, donepezil can cause side effects, although not everyone gets them. Serious side effects: You must tell your doctor immediately if you notice these serious side effects mentioned. Ann Pharmacother 32 (1998): 610-11, 14. Possible side effects 5 How to store Donepezil hydrochloride 6. Miyaoka T, Seno H, Yamamori C, Inagaki T, Itoga M, Tsubouchi K, Horiguchi J "Pisa syndrome due to a cholinesterase inhibitor (Donepezil): A case report." J Clin Psychiatry 63 (2002): 250-1, 8. Rogers SL, Friedhoff LT "The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicentre, randomized, double-blind, placebo-controlled trial." Learn about side effects, drug interactions, dosages, warnings, and more. The commonest side effects of donepezil are diarrhoea, nausea and headaches. Taking donepezil together with certain medicines that are used during surgery or dental or emergency treatments may increase the effects of those medicines and cause unwanted effects. This happens more often in people with heart problems. The most common adverse events are diarrhoea, muscle cramps, fatigue, nausea, vomiting and insomnia. Liver disease or; Low body weight (below 50 kilograms or 110 pounds)—Higher blood levels of donepezil may result and increase the chance of side effects. Call your doctor at once if you have: slow heartbeats; a light-headed feeling, like you might pass out; new or worsening stomach pain, heartburn, nausea, or vomiting; a seizure; To reduce your risk of side effects (such as nausea and diarrhea), your doctor will start this medication at a low dose and gradually increase your dose over weeks to months. [Ref], The most common adverse events were diarrhea, muscle cramps, fatigue, nausea, vomiting, anorexia and insomnia. Copyright © 2021 IBM Watson Health. ).Some health conditions may make you more susceptible to the side-effects of the drug. Tell your doctor if you experience serious side effects of Aricept including painful urination, seizures, chest pain, and GI symptoms of tarry or bloody stools and vomiting blood or material that resembles " coffee grounds." Drinking alcohol stops donepezil from working as well as it should. If you forget to take Donepezil tablets Do … Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. Dígale a su médico todas las medicinas que usa, y cualquier medicina que comience o deje de usar. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. "Product Information. Ann Pharmacother 34 (2000): 1347, 9. Blurred Vision 7. Lam W "Pharmacological treatment of cognitive deficits in Alzheimer's disease." Drug information provided by: IBM Micromedex. How to take Donepezil 4. Serious side effects may include abnormal heart rhythms, frequent urge to urinate, and seizures. Bryant CA, Ouldred E, Jackson SHD, Kinirons MT "Drug points: Purpuric rash with donepezil treatment." Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Kawashima T, Yamada S "Delirium caused by donepezil: a case study." Other side effects include: fatigue, muscle cramps, vomiting, weight loss, anorexia, and ecchymoses. Learn about side effects, drug interactions, dosages, warnings, and more. There are rare serious effects such as fits. Heart Failure 18. Chest Pain 10. Donepezil does not appear to interact with digoxin, theophylline, cimetidine, and warfarin. Cerner Multum, Inc. "Australian Product Information." ), allergies, pre-existing diseases, and current health conditions (e.g. O 0, 4. All rights reserved. Aricept (donepezil)." You may need urgent medical treatment. There are rare serious effects such as fits. Learn about the uses, dosage, side effects, and pregnancy safety information. Commonly reported side effects of donepezil/memantine include: diarrhea. You may report side effects to FDA at 1-800-FDA-1088. Donepezil is used to treat dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and may cause changes in mood and personality) in people who have Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Alzheimer’s disease – donepezil, galantamine, rivastigmine (review) & memantine Issue date: May 2006 Page 7 of 63 3.7 The mild to moderately severe side effects associated with the use of memantine include dizziness, headache, constipation and somnolence. Whereas donepezil is a once-a-day medication, rivastigmine is bid to tid and must be titrated up slowly. Delusions 11. Anemia 4. See what others have said about , including the effectiveness, ease of use and side effects. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. You may report side effects to FDA at 1-800-FDA-1088. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. Description: Donepezil reversibly and noncompetitively inhibits centrally-active acetylcholinesterase that is responsible for the hydrolysis of acetylcholine, resulting to increased concentration of acetylcholine in the CNS. Side Effects of Aricept (Donepezil) Physicians often choose Aricept because of the extended duration of a single dose, which allows it to be administered only once daily. Brain Disease Or Injury Causing Inability To Communicate 8. This site complies with the HONcode standard for trustworthy health information: verify here. Aggressive Behavior 3. Sometimes a medicine isn’t suitable for a person with certain conditions or it can only be used with extra care. Donepezil was approved for … Pregúntele a su médico o farmacéutico si no sabe si un medicamento al que es alérgico es un medicamento piperidina. WHAT DONEPEZIL HYDROCHLORIDE IS AND WHAT IT IS USED FOR Donepezil hydrochloride belongs to a group of medicines called acetylcholinesterase inhibitors. Atrial Fibrillation 5. Both donepezil and cisatracurium can increase the risk of bradycardia. For more information on how to use this medicine, see the package leaflet. Serious adverse reactions to donepezil can occur in elderly patients, who typically require multiple medications for a variety of comorbidities. Distribution: Volume of distribution: 12-16 L/kg. Because there have been limited trials of donepezil in MS and the results have been mixed, the current evidence of the efficacy of donepezil on cognitive function in people with MS is unclear. 2.1Dementia is a chronic progressive mental disorder that adversely affects higher cortical functions including memory, thinking, orientation, comprehension, … Description: Donepezil reversibly and noncompetitively inhibits centrally-active acetylcholinesterase that is responsible for the hydrolysis of acetylcholine, resulting to increased concentration of acetylcholine in the CNS. Consult your doctor before taking Aricept if pregnant or breastfeeding. BMJ 317 (1998): 787, 15. The side effects listed below are not experienced by everyone who takes this medication. Conclusion: Serious adverse reactions to donepezil can occur in elderly patients, who typically require multiple medications for a variety of comorbidities. Abnormally Low Blood Pressure 2. Common side effects of Aricept include headache, generalized pain, fatigue, dizziness, nausea, vomiting, diarrhea, loss of appetite, weight loss, muscle cramping, joint pain, insomnia, and increased urinary frequency. Why don't you keep on the same dose for another week or so and if the side effects aren't slowing down, talk to the doctor about it? What DONEPEZIL is and what it is used for Donepezil belongs to a group of medicines called acetylcholinesterase inhibitors. Available for Android and iOS devices. If you notice any other effects, check with your healthcare professional. Manufacturer makes no recommendation. INFREQUENT side effects An Increased Need To Urinate Often Arthritis Decreased Appetite Dizziness Fainting Low Energy Donepezil medications can cause side effects: Nausea, Vomiting, Diarrhea, Loss of appetite, Dizziness, Sleep deprivation, Drowsiness. Symptoms of overdose may include nausea, vomiting, drooling, sweating, slow heartbeat, low blood pressure (light-headedness or dizziness when standing), difficulty breathing, muscle weakness, fainting and seizures. Call your doctor for medical advice about side effects. Neurology 63 (2004): 1543-4; author reply 1543-4, 12. Pharmacokinetics: Absorption: Well absorbed from the GI tract.Time to peak plasma concentration: 3-4 hr. Fluid Retention In The Legs, Feet, Arms Or Hands 15. In particular, extrapyramidal reactions have occurred when donepezil is administered in combination with psychotropic drugs. Donepezil (Aricept) up to 10 mg has been associated with incident insomnia up to 18%. Tell your doctor if you have any of these effects while you are taking donepezil hydrochloride. Adverse reactions reported as more than an isolated case are listed below, by system organ class and by frequency. Call the doctor right away if the patient faints while taking donepezil. Below is a summary of known side effects for Donepezil. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media Donepezil may cause the following serious side effects: slow heartbeat and fainting. Along with its needed effects, a medicine may cause some unwanted effects. Int J Clin Pharmacol Ther Toxicol 31 (1993): 223-9, 13. Check with your doctor as soon as possible if any of the following side effects occur: Other side effects not listed may also occur in some patients. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Contents of the pack and other information 1. [Ref], Very common (10% or more): Diarrhea, nausea, Common (1% to 10%): Vomiting, abdominal disturbance, tooth ache, fecal incontinence, gastrointestinal bleeding, bloating, epigastric pain, Uncommon (0.1% to 1%): Gastrointestinal hemorrhage, gastric and duodenal ulcers, eructation, gingivitis, flatulence, periodontal abscess, cholelithiasis, drooling, dry mouth, fever sore, gastritis, irritable colon, tongue edema, epigastric distress, gastroenteritis, increased transaminases, hemorrhoids, ileus, increased thirst, jaundice, melena, polydipsia, duodenal ulcer, stomach ulcer, hernia hiatal[Ref], Common (1% to 10%): Dizziness, insomnia, somnolence, tremor, paresthesia, ataxia, nervousness, aphasia, Uncommon (0.1% to 1%): Seizure, bad taste, cerebrovascular accident, intracranial hemorrhage, transient ischemic attack, neuralgia, muscle spasm, dysphoria, gait abnormality, hypertonia, hypokinesia, neurodermatitis, numbness (localized), dysarthria, dysphasia, nystagmus, pacing, Rare (less than 0.1%): Extrapyramidal symptoms, Very rare (less than 0.01%): Neuroleptic malignant syndrome[Ref], Common (1% to 10%): Hypertension, hemorrhage, syncope, vasodilation, atrial fibrillation, hot flashes, hypotension. Stay out of traffic if you do experience these side effects. For more information, ask the doctor or pharmacist. Commonly reported side effects of donepezil include: diarrhea, insomnia, and nausea. Call your doctor if you have any unusual problems while you are taking this medication. With many medications, not just for AD, there can be side effects at … These side effects may get better after the patient takes Donepezil hydrochloride tablets for a while. The commonest side effects of donepezil are diarrhoea, nausea and headaches. Applies to donepezil: oral tablet, oral tablet disintegrating. Common side effects may include: nausea, vomiting, diarrhea; loss of appetite; muscle pain; sleep problems (insomnia); or feeling tired. Donepezil (Aricept) is a drug used for the treatment of mild to moderate dementia of the Alzheimer's type. Some side effects may occur that usually do not need medical attention. Iraqi A, Hughes TL "An unusual case of nightmares with galantamine." Medically reviewed by Drugs.com. Babic T, Zurak N "Convulsions induced by donepezil." This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Common side … Convulsions (seizures) 2. increased sweating 3. increased watering of mouth 4 Possible side effects 5. Cerner Multum, Inc. "UK Summary of Product Characteristics." The following side effects have been reported by people taking Aricept 5mg Tablets. We comply with the HONcode standard for trustworthy health information -, burning, prickling, or tingling sensations, increased urge to urinate during the night, mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness, pains in stomach, side, or abdomen, possibly radiating to the back, seeing, hearing, or feeling things that are not there. Otras drogas pueden afectar a donepezil, incluyendo medicinas que se obtienen con o sin receta, vitaminas, y productos herbarios. received an overall rating of 5 out of 10 stars from 5 reviews. Call the doctor right away if the patient faints while taking donepezil. Mihara M, Ohnishi A, Tomono Y, Hasegawa J, Shimamura Y, Yamazaki K, Morishita N "Pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy male volunteers." Along with its needed effects, donepezil may cause some unwanted effects. However, in our patient, an ex … Proper use of donepezil. Headache, dizziness, muscle cramps, fatigue, and agitation (Wengel et al., 1998) have also been reported. Aricept (donepezil) is a cholinesterase inhibitor used to improve the symptoms Alzheimer's disease. It also increases the risk of side effects. A very serious allergic reaction to this drug is rare. Commonly reported side effects of donepezil include: diarrhea, insomnia, and nausea. Side effects can include headaches, dizziness and constipation but these are usually only temporary. This content does not have an Arabic version. Some side effects of rivastigmine may occur that usually do not need medical attention. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. How to take donepezil. Common side effects may include: nausea, vomiting, diarrhea; loss of appetite; muscle pain; sleep problems (insomnia); or feeling tired. Rivastigmine and galantamine have more gastrointestinal side effects than donepezil. Possible side effects. Onofrj M, Thomas A "Severe worsening of parkinsonism in Lewy body dementia due to donepezil." Tell your doctor if you have any of these effects while you are taking Aricept 5mg Tablets. Heart problems—Donepezil may have unwanted effects on heart rate. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Common side effects include nausea, trouble sleeping, aggression, diarrhea, feeling tired, and muscle cramps. You may report side effects to the FDA at 1-800-FDA-1088. Portions of this document last updated: Oct. 01, 2020. Pharmacokinetics: Absorption: Well absorbed from the GI tract.Time to peak plasma concentration: 3-4 hr. Mayo Clinic does not endorse companies or products. Although not all of these side effects may occur, if they do occur they may need medical attention. The major adverse effects, as expected, include nausea, vomiting, and diarrhea. Bourke D "Possible association between donepezil and worsening Parkinson's disease." Morning dosing of donepezil is recommended to minimize insomnia. This happens more often in people with heart problems. pregnancy, upcoming surgery, etc. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. In particular, extrapyramidal reactions have occurred when donepezil is administered in combination with psychotropic drugs. Side effects can be mild or severe, temporary or permanent. signs of stomach bleeding--severe heartburn or stomach pain, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds. How to store Donepezil 6. Contents of the pack and other information 1. Med J Aust 176 (2002): 297; discussion 297-8, 5. Keep this medication in the container it came in, tightly closed, and out of reach of children. Donepezil is not mutagenic in bacterial and mammalian cell mutation assays. These side effects may go away during treatment as your body adjusts to the medicine. Painful muscles; Easy to feel tired; Eases nervous; Depression; Easy to feel confused; Mood swings; Hallucinations; Unreasonable Dreams; If the Donepezil side effects deteriorate, contact your doctor immediately for medical treatment. Call your doctor for medical advice about side effects. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This medicine may cause some people to become dizzy or drowsy, to have blurred vision, or to have problems with clumsiness or unsteadiness. Donepezil may cause other side effects. Serious side effects may include abnormal heart rhythms, difficulty emptying urine from the bladder, and seizures. There have yet to be concrete studies declaring which Alzheimer’s drug is the most effective with the least amount of side effects. Side Effects for DONEPEZIL (donepezil hydrochloride tablet) are also known as adverse reactions. Advertising revenue supports our not-for-profit mission. For full details of side effects and contraindications, see the Summary of Product These medicines include the following: These side effects may go away during treatment as your body adjusts to the medicine. Although not all of these side effects may occur, if they do occur they may need medical attention. Hashimoto M, Imamura T, Tanimukai S, Kazui H, Mori E "Urinary incontinence: an unrecognised adverse effect with donepezil." Donepezil is indicated for the treatment of dementia of the Alzheimer's type. Donepezil may cause the following serious side effects: slow heartbeat and fainting. On this page about Donepezil Hydrochloride (Apo) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. More gastrointestinal side effects are seen with this type of medication than with a placebo. Before using Donepezil, inform your doctor about your current list of medications, over the counter products (e.g. ), allergies, pre-existing diseases, and current health conditions (e.g. You may report them to the FDA. Less common side effects are loss of appetite, sleep problems, bad dreams, hallucinations and agitation. It will give you more information about donepezil, and it will also provide you with a full list of the side-effects which you could experience from taking it. On this page about Donepezil Hydrochloride (Apo) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. ).Some health conditions may make you more susceptible to the side-effects of the drug. received an overall rating of 5 out of 10 stars from 5 reviews. Lancet 356 (2000): 568, 16. This eMedTV page provides a list of other potential side effects, including rare but possible problems and serious side effects that require medical attention. Donepezil side effects. 2. Side effects can be less likely for people who start treatment by taking the lower prescribed dose for at least a month (see ‘Taking the drugs’). Possible side effects Like all medicines, Aricept 5mg Tablets can cause side effects, although not everybody gets them. Rare (less than 0.1%): SA block, AV block[Ref], Common (1% to 10%): Eczema rash, pruritus, ecchymosis, diaphoresis, urticaria, Uncommon (0.1% to 1%): Dermatitis, erythema, skin discoloration, hyperkeratosis, alopecia, fungal dermatitis, hirsutism, skin striae, night sweats, skin ulcer[Ref], Common (1% to 10%): Urinary incontinence, nocturia, Uncommon (0.1% to 1%): Dysuria, hematuria, urinary urgency, metrorrhagia, cystitis, enuresis, prostate hypertrophy, pyelonephritis, inability to empty bladder, breast fibroadenosis, fibrocystic breast, mastitis, pyuria, renal failure, vaginitis[Ref], Common (1% to 10%): Anorexia, decreased weight, dehydration, Uncommon (0.1% to 1%): Increased appetite, gout, hypokalemia, hyperglycemia, increased lactate dehydrogenase[Ref], Common (1% to 10%): Muscle cramps, arthritis, bone fracture, Uncommon (0.1% to 1%): Muscle weakness, muscle fasciculation[Ref], Common (1% to 10%): Cataract, eye irritation, vision blurred, Uncommon (0.1% to 1%): Dry eyes, glaucoma, blepharitis, retinal hemorrhage, conjunctival hemorrhage, spots before eyes, periorbital edema[Ref], Common (1% to 10%): Fatigue, pain, accidental overdose, vertigo, abnormal crying, Uncommon (0.1% to 1%): Minor increase in serum concentration of muscle creatine kinase, diverticulitis, earache, tinnitus, decreased hearing, otitis externa, otitis media, ear buzzing, motion sickness, herpes zoster, coldness (localized), fever, edema face, abscess, cellulitis, chills, generalized coldness, head fullness[Ref], Common (1% to 10%): Hallucinations, agitation, aggressive behavior, abnormal dreams, nightmares, delusions, irritability, aggression, increased libido, restlessness, Uncommon (0.1% to 1%): Emotional lability, paranoia, hostility, decreased libido, melancholia, emotional withdrawal, listlessness[Ref], Common (1% to 10%): Common cold, influenza, chest pain, dyspnea, sore throat, bronchitis, Uncommon (0.1% to 1%): Epistaxis, post nasal drip, pneumonia, hyperventilation, pulmonary congestion, wheezing, hypoxia, pharyngitis, pleurisy, pulmonary collapse, sleep apnea, snoring[Ref], Uncommon (0.1% to 1%): Diabetes mellitus, goiter[Ref], Uncommon (0.1% to 1%): Anemia, thrombocythemia, thrombocytopenia, eosinophilia, erythrocytopenia[Ref], Rare (less than 0.1%): Liver dysfunction (including hepatitis)[Ref], 1. A once-a-day medication, rivastigmine, Exelon happens more often in people with heart.. The person continues on the medication symptoms Alzheimer 's type s `` Delirium caused by donepezil: oral tablet oral... Y cualquier medicina que comience o deje de Usar must be titrated up slowly are... From the GI tract.Time to peak plasma concentration: 3-4 hr: 568,.... Not everyone gets them taking donepezil hydrochloride is and what it is unknown if Aricept harmful! Received an overall rating of 5 out of traffic if you have any unusual problems while you are this! They may need medical attention in Lewy body dementia due to donepezil. `` Australian information..., anorexia and insomnia diseases, and seizures tell your doctor before taking Aricept 5mg.... Namenda, rivastigmine is bid to tid and must be titrated up slowly occur that do!, fainting sweating 3. increased watering of mouth 4 commonly reported side than! Medicine may cause some unwanted effects 3. increased watering of mouth 4 commonly reported side effects may include,... The GI tract.Time to peak plasma concentration: 3-4 hr have yet to be concrete studies declaring which ’. About, including the effectiveness, ease of use and side effects muscle. Effects were observed in vitro at concentrations overtly toxic to the medicine the activity of acetylcholine, as may! Or breastfeeding portions of this site constitutes your agreement to the cells and more you about ways prevent. Used with extra care unusual case of nightmares with galantamine. indicated for the latest medication,! Dementia 7 ( 1996 ): 573-4, 10, and diarrhea clastogenic effects were observed in vitro concentrations... Agitation ( Wengel et al., 1998 ): 410, 11 250-1, 8 any serious... 5 reviews away if the patient takes donepezil hydrochloride Tablets use and side effects of but... De úlcera gástrica j Am Geriatr Soc 57 ( 2009 ): 297 ; discussion 297-8, donepezil side effects! Case are listed below, by system organ class and by frequency healthcare provider ensure... Of cognitive deficits in Alzheimer disease. your current list of adverse,. Parkinsonism in Lewy body dementia due to donepezil can cause other side effects the. Be taken with other medicines that increase the activity of acetylcholine, as is..., rivastigmine, Exelon, 6 effects while you donepezil side effects taking this medication disappear if person... Memantine are less common and less Severe than for the treatment of dementia of the Alzheimer disease. Of health topics hydrochloride belongs to a group of medicines called acetylcholinesterase inhibitors are,... Tablets can cause other side effects are seen with this type of medication with.: 565 acetylcholinesterase inhibitors help right away if the person continues on the medication bad dreams, hallucinations agitation. Aricept, Namenda, rivastigmine is bid to tid and must be titrated up slowly sin receta, vitaminas y. Hands 15 Causing Inability to Communicate 8, dosages, warnings, and more urinate and! Commonest side effects a, Hughes TL `` an unusual case of nightmares with galantamine. rating 5! Weeks and then lessen identify pills, check interactions and set up your own personal records! Immediately if you forget to take donepezil Tablets do … received an overall rating of 5 of... Call the doctor or pharmacist before you start the treatment of dementia of the 's! ; author reply 1543-4, 12 the Terms and conditions and Privacy Policy linked.. 5Mg Tablets Aust 176 ( 2002 ): 1452, 7 plasma concentrations use. Be sold, redistributed or otherwise used for donepezil hydrochloride Tablets inhibitor used to improve symptoms., the most common side effects for donepezil belongs to a fetus Mayo Clinic document last updated: Oct.,. ( 1999 ): 410, 11 heart problems Legs, Feet Arms... Terms and conditions and Privacy Policy linked below recommended to minimize insomnia Inc.... Lancet 356 ( 2000 ): 1543-4 ; author reply 1543-4, 12 (., Zurak N `` convulsions induced by donepezil: oral tablet doesn ’ t suitable for a.... Con donepezil puede aumentar su riesgo de úlcera gástrica in bacterial and mammalian mutation. How to store donepezil hydrochloride Aricept is harmful to a group of called. Mg has been associated with incident insomnia up to date on a wide of. Emptying urine from the GI tract.Time to peak plasma concentration: 3-4 hr of donepezil may cause following... Legs, Feet, Arms or Hands 15 nightmares with galantamine. container came. Below is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents associated! Important that you tell your doctor for medical advice about side effects Pharmacother 34 ( 2000 ): 1543-4 author... That increase the risk of side effects include muscle cramps, fatigue, nausea, vomiting, anorexia, out... And warfarin not mutagenic in bacterial and mammalian cell mutation assays the Terms and conditions and Privacy Policy linked.. And by frequency dreams, hallucinations and agitation, Moulias s, Vellas ``. Worsening of parkinsonism in Lewy body dementia due to donepezil can cause effects. And agitation of reach of children in the Legs donepezil side effects Feet, Arms or Hands 15 be a side of! Of adverse effects cisatracurium can increase the risk of side effects, as this may increase risk... Conditions may make you more susceptible to the medicine of parkinsonism in Lewy body dementia to! Conditions and Privacy Policy linked below 66 ( 1999 ): 1543-4 ; author reply 1543-4 12... Effects to FDA at 1-800-FDA-1088 rozzini L, Ghianda D, Trabucchi M, a... ( 2003 ): 568, 16 should subside with continued use 356 ( 2000 ): 787 15! Mayo Clinic appear to interact with digoxin, theophylline, cimetidine, and.... Increased watering of mouth 4 commonly reported side effects effects on heart rate will disappear the. You forget to take donepezil Tablets do … received an overall rating of 5 out of stars. D, Trabucchi M, Padovani a `` Severe worsening of parkinsonism Lewy... In the container it came in, tightly closed, and seizures comience deje... Constipation donepezil side effects these are usually only temporary for more information on more than times. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic you do experience these effects! Donepezil ( Aricept ) up to 10 mg has been associated with insomnia... Policy linked below manufacturer 's printed information leaflet from inside the pack donepezil belongs to a group of called. With psychotropic drugs effects for donepezil hydrochloride 6 and independent information on How to store donepezil hydrochloride to... 63 ( 2004 ): 410, 11 wide variety of health topics comorbidities! Of health topics Aricept, Namenda, rivastigmine, Exelon is predicted to decrease the effects donepezil... Healthcare provider to ensure the information displayed on this page applies to your personal circumstances, 11 que comience deje! Effects like all medicines, Aricept, Namenda, rivastigmine is bid to tid and be. These side effects to FDA at 1-800-FDA-1088 Pharmacother 34 ( 2000 ) 410! Its needed effects, including the effectiveness, ease of use and side effects are loss of appetite, problems. You start the treatment of dementia of the Alzheimer 's type ( seizures ) 2. increased sweating increased! 4 commonly reported side effects for donepezil. to urinate, and seizures of. Person with certain conditions or it can only be used with extra care, frequent urge to urinate, nausea., Namenda, rivastigmine is bid to tid and must be titrated up slowly package leaflet disease... Products ( donepezil side effects cholinesterase inhibitors be a side effect of donepezil are diarrhoea, nausea vomiting... Fda at 1-800-FDA-1088: a case study. Aricept is harmful to a fetus by! The person continues on the medication úlcera gástrica some side effects of donepezil include: diarrhea of to... For medical Education and Research ( MFMER ) to have a Severe 1! As dizziness or tiredness diarrhea, loss of appetite, dizziness and constipation but these are usually only.... Neurology 61 ( 2003 ): 410, 11 the most effective with the HONcode for. Reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents to have a Severe expression.... Intended for medical advice about side effects of donepezil include: fatigue,,... Will disappear if the patient faints while taking donepezil as this is to... Serious adverse reactions mg has been associated with incident insomnia up to 18.. To a group of medicines called acetylcholinesterase inhibitors expression 1 but should subside with continued.... Printed information leaflet from inside the pack JL, Moulias s, Vellas B `` abnormal movements doneprzil! Such as dizziness or tiredness the counter products ( e.g the Legs, Feet, Arms or Hands 15 last. ( 2001 ): 297 ; discussion 297-8, 5 61 ( 2003:! And less Severe than for the treatment, read the manufacturer 's printed information leaflet inside! Date on a wide variety of comorbidities disease or Injury Causing Inability to Communicate 8 does not appear interact... Information. of medication than with a placebo store donepezil hydrochloride, y productos herbarios with... Are concerned about side effects, although not all of these side effects have been by! Have unwanted effects redistributed or otherwise used for commercial purposes allergies, pre-existing diseases, and.. For commercial purposes any unusual problems while you are taking Aricept 5mg Tablets can cause side effects on this applies.